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Further mechanistic studies showed that NNMTi increases intracellular NAD levels and activates the SIRT1 pathway by inhibiting NNMT, thereby suppressing the transcription of adipogenic genes and preventing the maturation of preadipocytes.This research provides a new perspective for understanding the molecular mechanism of adipocyte differentiation, confirms the key role of NNMTi in regulating adipogenesis, and lays a foundation for subsequent obesity intervention studies

Bowers, R

Choline is a macronutrient that is responsible for normal liver and nerve functioning, brain development, muscle movement, supporting energy levels, and maintaining a healthy metabolism

Biochem Mol Biol Int